Uveal Melanoma Therapeutics Pipeline Analysis 2018 322 views |
7/26/2019, Uveal melanoma is the most common primary malignant tumour of intraocular malignancy, arises from melanocytes in the iris, and ciliary body. read more |
|
Tuberous Sclerosis Therapeutics Pipeline Analysis 2018 336 views |
7/26/2019, Tuberous sclerosis, also known as tuberous sclerosis complex, is a genetic disorder characterized by the growth of numerous noncancerous (benign) tumors in many parts of the body. read more |
|
Cathepsin K Inhibitors Therapeutics Pipeline Analysis 2019 336 views |
7/26/2019, Cathepsin K is a protease enzyme which is coded by CTSK gene. The function associated with the gene involves bone remodelling and resorption. Cathepsin K is a member of peptidase C1 protein family and expressed mainly in osteoclasts. read more |
|
Adenosine 5-Monophosphate Activated Protein Kinase (AMPK) Modulators Therapeutics Pipeline Analysis 339 views |
7/26/2019, Adenosine 5-monophosphate activated protein kinase (AMPK) plays an important role in regulation of homeostasis. Dysregulation of AMPK can result in many diseases which includes obesity and type 2 diabetes. read more |
|
Aurora Kinase Inhibitor Therapeutics Pipeline Analysis 2018 335 views |
7/26/2019, Aurora kinase are proteins that function as mitotic regulators and are aberrantly expressed in cancerous cells. Aurora kinase inhibitors target these aberrantly expressed regulators, provides genetic stability and prevents tumorigenesis. read more |
|
Angiopoietin (ANG) Inhibitors Therapeutics Pipeline Analysis 2019 342 views |
7/26/2019, Angiopoietin (ANG) receptor plays a crucial role in regulation of vascular permeability and pathological vascular remodelling during tumour angiogenesis, metastasis and inflammation. read more |
|
Spleen Tyrosine Kinase (Syk) Inhibitor Therapeutics Pipeline Analysis 2018 336 views |
7/26/2019, Spleen tyrosine kinase (Syk) is a protein that belongs to the family of tyrosine kinases with an ability to initiate the inflammatory responses, by connecting immune cell receptors to intracellular signaling pathways. read more |
|
Glycogen Synthase Kinase 3 Beta (GSK-3ß) Inhibitors Therapeutics- Pipeline Analysis 2019 334 views |
7/26/2019, Glycogen synthase kinase 3 beta (GSK-3ß) is an attractive target for the treatment of psychiatric disorders and neurodegenerative diseases. read more |
|
Hepatocyte Growth Factor (HGF) Inhibitor Therapeutics - Pipeline Analysis 2019 345 views |
7/26/2019, Hepatocyte growth factor (HGF) is secreted by human pancreatic stellate cells and present predominantly on cancer cells. Thus, HGF inhibitors has emerged as an effective therapy in preventing local tumor growth. read more |
|
Interleukin 8 Inhibitors Therapeutics - Pipeline Analysis 2019 332 views |
7/26/2019, Interleukin 8 is a chemokine produced by various immune cells. They promote angiogenesis, proliferation and development of cancerous cells. read more |
|